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KMID : 1038120220550040558
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Clinical Endoscopy
2022 Volume.55 No. 4 p.558 ~ p.563
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Bispectral index-guided propofol sedation during endoscopic ultrasonography
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Okamoto Ayana
Kamata Ken
Miyata Takeshi
Yoshikawa Tomoe
Ishikawa Rei
Yamazaki Tomohiro
Nakai Atsushi
Komoto Shunsuke
Minaga Kosuke
Yamao Kentaro
Takenaka Mamoru
Chiba Yasutaka
Sakurai Toshiharu
Nishida Naoshi
Kitano Masayuki
Kudo Masatoshi
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Abstract
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Background/Aims: Bispectral index (BIS) monitors process and display electroencephalographic data are used to assess the depth of anesthesia. This study retrospectively evaluated the usefulness of BIS monitoring during endoscopic ultrasonography (EUS).
Methods: This study included 725 consecutive patients who underwent EUS under sedation with propofol. BIS monitoring was used in 364 patients and was not used in 361. The following parameters were evaluated: (1) median dose of propofol; (2) respiratory and circulatory depression; (3) occurrence of body movements; (4) awakening score >8 at the time; and (5) awakening score 2 hours after leaving the endoscopy room.
Results: The BIS group received a significantly lower median dose of propofol than the non-BIS group (159.2 mg vs. 167.5 mg; p=0.015) in all age groups. For patients aged ≥75 years, the reduction in heart rate was significantly lower in the BIS group than in the non-BIS group (1.2% vs. 9.1%; p=0.023). Moreover, the occurrence of body movements was markedly lower in the BIS group than in the non-BIS group (8.5% vs. 39.4%; p<0.001).
Conclusions: During EUS examination, BIS monitoring is useful for maintaining a constant depth of anesthesia, especially in patients 75 years of age or older.
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KEYWORD
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Consciousness monitors, Intravenous anesthesia, Endosonography, Midazolam, Propofol
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